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Mastocytosis is a very rare disorder affecting mast cells. In people who do not have mastocytosis, mast cells are triggered during allergy attacks. They release substances that cause the symptoms of allergy. These substances are stored in granules within the mast cells and are released into the body during an allergy attack. This is called ‘mast cell degranulation.’

This leaflet is for patients with mastocytosis who are preparing to have an anaesthetic. It will also be useful to anaesthetists and other healthcare professionals who would like an update on safe anaesthesia practice for patients with mastocytosis.